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Opening of tandem calponin homology domains regulates their affinity for F-actin

Many actin-binding proteins contain calponin homology (CH) domains, but the manner in which these domains interact with F-actin has been controversial. Crystal structures have shown the tandem CH domains of α-actinin to be in a compact, closed conformation, but the interpretations of complexes of su...

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Detalhes bibliográficos
Main Authors: Galkin, Vitold E., Orlova, Albina, Salmazo, Anita, Djinovic-Carugo, Kristina, Egelman, Edward H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921939/
https://ncbi.nlm.nih.gov/pubmed/20383143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1789
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