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Steric regulation of tandem calponin homology domain actin-binding affinity

Tandem calponin homology (CH1–CH2) domains are common actin-binding domains in proteins that interact with and organize the actin cytoskeleton. Despite regions of high sequence similarity, CH1–CH2 domains can have remarkably different actin-binding properties, with disease-associated point mutants k...

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Podrobná bibliografie
Vydáno v:Mol Biol Cell
Hlavní autoři: Harris, Andrew R., Belardi, Brian, Jreij, Pamela, Wei, Kathy, Shams, Hengameh, Bausch, Andreas, Fletcher, Daniel A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938246/
https://ncbi.nlm.nih.gov/pubmed/31693446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-06-0317
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