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The impact of microfluidic mixing of triblock micelleplexes on in vitro/in vivo gene silencing and intracellular trafficking

The triblock copolymer polyethylenimine-polycaprolactone-polyethylene glycol (PEI-PCL-PEG) has been shown to spontaneously assemble into nano-sized particulate carriers capable of complexing with nucleic acids for gene delivery. The objective of this study was to investigate micelleplex characterist...

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Detalhes bibliográficos
Publicado no:Nanotechnology
Main Authors: Feldmann, Daniel P, Xie, Yuran, Jones, Steven K, Yu, Dongyue, Moszczynska, Anna, Merkel, Olivia M
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539944/
https://ncbi.nlm.nih.gov/pubmed/28488596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1361-6528/aa6d15
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