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Characterization of Dopaminergic System in the Striatum of Young Adult Park2(−/−) Knockout Rats
Mutations in parkin gene (Park2) are linked to early-onset autosomal recessive Parkinson’s disease (PD) and young-onset sporadic PD. Park2 knockout (PKO) rodents; however, do not display neurodegeneration of the nigrostriatal pathway, suggesting age-dependent compensatory changes. Our goal was to ex...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5784013/ https://ncbi.nlm.nih.gov/pubmed/29367643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18526-0 |
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