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Microfluidic Assembly of siRNA-Loaded Micelleplexes for Tumor Targeting in an Orthotopic Model of Ovarian Cancer

The use of cationic polymers to interact with negatively charged siRNA via charge complexation to form polyelectrolyte complexes has been widely studied ever since the 1998 report on RNA interference. These polyelectrolyte complex formulations aim to overcome the many pitfalls associated with the us...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Feldmann, Daniel P., Jones, Steven, Douglas, Kirk, Shields, Anthony F., Merkel, Olivia M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6853190/
https://ncbi.nlm.nih.gov/pubmed/31099014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-9220-1_24
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