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Klotho, an antiaging molecule, attenuates oxidant-induced alveolar epithelial cell mtDNA damage and apoptosis
Alveolar epithelial cell (AEC) apoptosis and inadequate repair resulting from “exaggerated” lung aging and mitochondrial dysfunction are critical determinants promoting lung fibrosis. α-Klotho, which is an antiaging molecule that is expressed predominantly in the kidney and secreted in the blood, ca...
Enregistré dans:
| Publié dans: | Am J Physiol Lung Cell Mol Physiol |
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| Auteurs principaux: | , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5538874/ https://ncbi.nlm.nih.gov/pubmed/28428174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00063.2017 |
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