Klotho, an antiaging molecule, attenuates oxidant-induced alveolar epithelial cell mtDNA damage and apoptosis

Alveolar epithelial cell (AEC) apoptosis and inadequate repair resulting from “exaggerated” lung aging and mitochondrial dysfunction are critical determinants promoting lung fibrosis. α-Klotho, which is an antiaging molecule that is expressed predominantly in the kidney and secreted in the blood, ca...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Kim, Seok-Jo, Cheresh, Paul, Eren, Mesut, Jablonski, Renea P., Yeldandi, Anjana, Ridge, Karen M., Budinger, G. R. Scott, Kim, Dong-Hyun, Wolf, Myles, Vaughan, Douglas E., Kamp, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538874/
https://ncbi.nlm.nih.gov/pubmed/28428174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00063.2017
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