טוען...
Targeted inactivation of copper transporter Atp7b in hepatocytes causes liver steatosis and obesity in mice
Copper-transporting ATPase 2 (ATP7B) is essential for mammalian copper homeostasis. Mutations in ATP7B result in copper accumulation, especially in the liver, and cause Wilson disease (WD). The major role of hepatocytes in WD pathology is firmly established. It is less certain whether the excess Cu...
שמור ב:
| הוצא לאור ב: | Am J Physiol Gastrointest Liver Physiol |
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| Main Authors: | , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Physiological Society
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5538836/ https://ncbi.nlm.nih.gov/pubmed/28428350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00312.2016 |
| תגים: |
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