טוען...

Targeted inactivation of copper transporter Atp7b in hepatocytes causes liver steatosis and obesity in mice

Copper-transporting ATPase 2 (ATP7B) is essential for mammalian copper homeostasis. Mutations in ATP7B result in copper accumulation, especially in the liver, and cause Wilson disease (WD). The major role of hepatocytes in WD pathology is firmly established. It is less certain whether the excess Cu...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Am J Physiol Gastrointest Liver Physiol
Main Authors: Muchenditsi, Abigael, Yang, Haojun, Hamilton, James P., Koganti, Lahari, Housseau, Franck, Aronov, Lisa, Fan, Hongni, Pierson, Hannah, Bhattacharjee, Ashima, Murphy, Robert, Sears, Cynthia, Potter, James, Wooton-Kee, Clavia R., Lutsenko, Svetlana
פורמט: Artigo
שפה:Inglês
יצא לאור: American Physiological Society 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538836/
https://ncbi.nlm.nih.gov/pubmed/28428350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00312.2016
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