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Myosin Vb mediates Cu(+) export in polarized hepatocytes

The cellular machinery responsible for Cu(+)-stimulated delivery of the Wilson-disease-associated protein ATP7B to the apical domain of hepatocytes is poorly understood. We demonstrate that myosin Vb regulates the Cu(+)-stimulated delivery of ATP7B to the apical domain of polarized hepatic cells, an...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Gupta, Arnab, Schell, Michael J., Bhattacharjee, Ashima, Lutsenko, Svetlana, Hubbard, Ann L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813291/
https://ncbi.nlm.nih.gov/pubmed/26823605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.175307
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