Disrupted prenatal RNA processing and myogenesis in congenital myotonic dystrophy

Myotonic dystrophy type 1 (DM1) is a CTG microsatellite expansion (CTG(exp)) disorder caused by expression of CUG(exp) RNAs. These mutant RNAs alter the activities of RNA processing factors, including MBNL proteins, leading to re-expression of fetal isoforms in adult tissues and DM1 pathology. While...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Genes Dev
Glavni autori: Thomas, James D., Sznajder, Łukasz J., Bardhi, Olgert, Aslam, Faaiq N., Anastasiadis, Zacharias P., Scotti, Marina M., Nishino, Ichizo, Nakamori, Masayuki, Wang, Eric T., Swanson, Maurice S.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2017
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538435/
https://ncbi.nlm.nih.gov/pubmed/28698297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.300590.117
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items