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Key analogs of a uniquely potent synthetic vinblastine that contain modifications of the C20′ ethyl substituent
A key series of vinblastine analogs 7–13, which contain modifications to the C20′ ethyl group, was prepared with use of two distinct synthetic approaches that provide modifications of the C20′ side chain containing linear and cyclized alkyl groups or added functionalized substituents. Their examinat...
Shranjeno v:
| izdano v: | Bioorg Med Chem Lett |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5538265/ https://ncbi.nlm.nih.gov/pubmed/28551101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2017.05.058 |
| Oznake: |
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