Yüklüyor......
Vinblastine 20’ Amides: Synthetic Analogs That Maintain or Improve Potency and Simultaneously Overcome Pgp-derived Efflux and Resistance
A series of 180 vinblastine 20’ amides were prepared in three steps from commercially available starting materials, systematically exploring a typically inaccessible site in the molecule enlisting a powerful functionalization strategy. Clear structure–activity relationships and a structural model we...
Kaydedildi:
| Yayımlandı: | J Med Chem |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2017
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5599373/ https://ncbi.nlm.nih.gov/pubmed/28857558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.7b00958 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|