Homocysteine induces mitochondrial dysfunction involving the crosstalk between oxidative stress and mitochondrial pSTAT3 in rat ischemic brain

Homocysteine (Hcy) has been shown to have a neurotoxic effect on ischemic brain cells; however, the underlying mechanisms remain incompletely understood. Here, we examined whether Hcy treatment influences mitochondria injury, oxidative stress, and mitochondrial STAT3 (mitoStat3) expression in rat is...

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Detalhes bibliográficos
Publicado no:Sci Rep
Principais autores: Chen, Shuang, Dong, Zhiping, Zhao, Yaqian, Sai, Na, Wang, Xuan, Liu, Huan, Huang, Guowei, Zhang, Xumei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537278/
https://ncbi.nlm.nih.gov/pubmed/28761070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07112-z
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