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Homocysteine enhances neural stem cell autophagy in in vivo and in vitro model of ischemic stroke

The elevated level of the amino acid metabolite homocysteine (Hcy) is known as a risk factor for ischemic stroke. The molecular mechanisms responsible for neurotoxicity of Hcy remain largely unknown in ischemic brains. The previous studies have shown that Hcy decreases the proliferation and viabilit...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wang, Mengying, Liang, Xiaoshan, Cheng, Man, Yang, Liu, Liu, Huan, Wang, Xuan, Sai, Na, Zhang, Xumei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6646339/
https://ncbi.nlm.nih.gov/pubmed/31332165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1798-4
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