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Homocysteine enhances neural stem cell autophagy in in vivo and in vitro model of ischemic stroke

The elevated level of the amino acid metabolite homocysteine (Hcy) is known as a risk factor for ischemic stroke. The molecular mechanisms responsible for neurotoxicity of Hcy remain largely unknown in ischemic brains. The previous studies have shown that Hcy decreases the proliferation and viabilit...

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Bibliografische gegevens
Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Wang, Mengying, Liang, Xiaoshan, Cheng, Man, Yang, Liu, Liu, Huan, Wang, Xuan, Sai, Na, Zhang, Xumei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6646339/
https://ncbi.nlm.nih.gov/pubmed/31332165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1798-4
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