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Reversal of homocysteine-induced neurotoxicity in rat hippocampal neurons by astaxanthin: evidences for mitochondrial dysfunction and signaling crosstalk

Elevated plasma level of homocysteine (Hcy) represents an independent risk for neurological diseases, and induction of oxidative damage is considered as one of the most important pathomechanisms. Astaxanthin (ATX) exhibits strong antioxidant activity in kinds of experimental models. However, the pot...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Wang, Xian-jun, Chen, Wang, Fu, Xiao-ting, Ma, Jin-kui, Wang, Mei-hong, Hou, Ya-jun, Tian, Da-chen, Fu, Xiao-yan, Fan, Cun-dong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197197/
https://ncbi.nlm.nih.gov/pubmed/30374413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-018-0114-x
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