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Simultaneous Delivery of Hydrophobic Small Molecules and siRNA Using Sterosomes to Direct Mesenchymal Stem Cell Differentiation for Bone Repair

The use of small molecular drugs with gene manipulation offers synergistic therapeutic efficacy by targeting multiple signaling pathways for combined treatment. Stimulation of mesenchymal stem cells (MSCs) with osteoinductive small molecule phenamil combined with suppression of noggin is a promising...

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Detalhes bibliográficos
Publicado no:Acta Biomater
Main Authors: Cui, Zhong-Kai, Sun, Justin A., Baljon, Jessalyn J., Fan, Jiabing, Kim, Soyon, Wu, Benjamin M., Aghaloo, Tara, Lee, Min
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537024/
https://ncbi.nlm.nih.gov/pubmed/28578107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2017.05.057
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