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Conjugation and Evaluation of Small Hydrophobic Molecules to Triazole-Linked siRNAs
[Image: see text] Short interfering RNAs (siRNAs) have tremendous potential as a new class of next-generation therapeutics; however, their progress is lagging due to issues related to stability, biodistribution, and cell-membrane permeability. To overcome these issues, there is widespread interest i...
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| 出版年: | ACS Med Chem Lett |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Chemical
Society
2014
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| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4329592/ https://ncbi.nlm.nih.gov/pubmed/25699137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500260j |
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