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Hydrophobization and bioconjugation for enhanced siRNA delivery and targeting

RNA interference (RNAi) is an evolutionarily conserved process by which double-stranded small interfering RNA (siRNA) induces sequence-specific, post-transcriptional gene silencing. Unlike other mRNA targeting strategies, RNAi takes advantage of the physiological gene silencing machinery. The potent...

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Dettagli Bibliografici
Autori principali: De Paula, Daniel, Bentley, M. Vitória L.B., Mahato, Ram I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1831859/
https://ncbi.nlm.nih.gov/pubmed/17329355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.459807
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