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Hydrophobization and bioconjugation for enhanced siRNA delivery and targeting
RNA interference (RNAi) is an evolutionarily conserved process by which double-stranded small interfering RNA (siRNA) induces sequence-specific, post-transcriptional gene silencing. Unlike other mRNA targeting strategies, RNAi takes advantage of the physiological gene silencing machinery. The potent...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1831859/ https://ncbi.nlm.nih.gov/pubmed/17329355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.459807 |
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