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Smoothened agonist sterosome immobilized hybrid scaffold for bone regeneration

Biomaterial delivery of bioactive agents and manipulation of stem cell fate are an attractive approach to promote tissue regeneration. Here, smoothened agonist sterosome is developed using small-molecule activators [20S-hydroxycholesterol (OHC) and purmorphamine (PUR)] of the smoothened protein in t...

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Bibliografiske detaljer
Udgivet i:Sci Adv
Main Authors: Lee, Chung-Sung, Kim, Soyon, Fan, Jiabing, Hwang, Hee Sook, Aghaloo, Tara, Lee, Min
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7176430/
https://ncbi.nlm.nih.gov/pubmed/32494652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz7822
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