WNK-Cab39-NKCC1 signaling increases the susceptibility to ischemic brain damage in hypertensive rats

With-no-lysine kinase (WNK) and Na(+)-K(+)-2Cl(−) cotransporter 1 (NKCC1) are involved in the pathogenesis of hypertension. In this study, we investigated the WNK-NKCC1 signaling pathway in spontaneously hypertensive rats (SHR) and their associated susceptibility to stroke injury. Basal NKCC1 protei...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Bhuiyan, Mohammad Iqbal H, Song, Shanshan, Yuan, Hui, Begum, Gulnaz, Kofler, Julia, Kahle, Kristopher T, Yang, Sung-Sen, Lin, Shih-Hua, Alper, Seth L, Subramanya, Arohan R, Sun, Dandan
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536788/
https://ncbi.nlm.nih.gov/pubmed/27798271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X16675368
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