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Generation of WNK1 knockout cell lines by CRISPR/Cas-mediated genome editing
Sodium-coupled SLC12 cation chloride cotransporters play important roles in cell volume and chloride homeostasis, epithelial fluid secretion, and renal tubular salt reabsorption. These cotransporters are phosphorylated and activated indirectly by With-No-Lysine (WNK) kinases through their downstream...
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| Publicado no: | Am J Physiol Renal Physiol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4329490/ https://ncbi.nlm.nih.gov/pubmed/25477473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00612.2014 |
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