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WNK1-OSR1 kinase-mediated phospho-activation of Na(+)-K(+)-2Cl(-) cotransporter facilitates glioma migration
BACKGROUND: The bumetanide (BMT)-sensitive Na(+)-K(+)-2Cl(-) cotransporter isoform 1 (NKCC1) maintains cell volume homeostasis by increasing intracellular K(+) and Cl(-) content via regulatory volume increase (RVI). Expression levels of NKCC1 positively correlate with the histological grade and seve...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3936893/ https://ncbi.nlm.nih.gov/pubmed/24555568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-31 |
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