An ordered pathway of snRNP binding during mammalian pre-mRNA splicing complex assembly.

We have studied the assembly, composition and structure of splicing complexes using biotin-avidin affinity chromatography and RNase protection assays. We find that U1, U2, U4, U5 and U6 snRNPs associate with the pre-mRNA and are in the mature, functional complex. Association of U1 snRNP with the pre...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Bindereif, A, Green, M R
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 1987
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC553648/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2959470/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1987.tb02520.x
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