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An ordered pathway of snRNP binding during mammalian pre-mRNA splicing complex assembly.

We have studied the assembly, composition and structure of splicing complexes using biotin-avidin affinity chromatography and RNase protection assays. We find that U1, U2, U4, U5 and U6 snRNPs associate with the pre-mRNA and are in the mature, functional complex. Association of U1 snRNP with the pre...

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Bibliografiska uppgifter
I publikationen:EMBO J
Huvudupphovsmän: Bindereif, A, Green, M R
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 1987
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC553648/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2959470/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1987.tb02520.x
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