Targeting PI3K and RAD51 in Barrett’s Adenocarcinoma: Impact on DNA Damage Checkpoints, Expression Profile and Tumor Growth

Phosphatidylinositol 3-kinase (PI3K)/v-akt murine thymoma viral oncogene homolog 1 (AKT) signaling in cancer is implicated in various survival pathways including regulation of recombinase (RAD51). In this study, we evaluated PI3K and RAD51 as targets in Barrett’s adenocarcinoma (BAC) cells both in v...

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Pubblicato in:Cancer Genomics Proteomics
Autori principali: PAL, JAGANNATH, FULCINITI, MARIATERESA, NANJAPPA, PURU, BUON, LEUTZ, TAI, YU-TZU, TASSONE, PIERFRANCESCO, MUNSHI, NIKHIL C., SHAMMAS, MASOOD A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536098/
https://ncbi.nlm.nih.gov/pubmed/22399496
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