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TGF-β-Dependent Growth Arrest and Cell Migration in Benign and Malignant Breast Epithelial Cells Are Antagonistically Controlled by Rac1 and Rac1b

Despite improvements in diagnosis and treatment, breast cancer is still the most common cancer type among non-smoking females. TGF-β can inhibit breast cancer development by inducing cell cycle arrest in both, cancer cells and, as part of a senescence program in normal human mammary epithelial cells...

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Publicat a:Int J Mol Sci
Autors principals: Melzer, Catharina, von der Ohe, Juliane, Hass, Ralf, Ungefroren, Hendrik
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536062/
https://ncbi.nlm.nih.gov/pubmed/28726720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18071574
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