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TGF-β-Dependent Growth Arrest and Cell Migration in Benign and Malignant Breast Epithelial Cells Are Antagonistically Controlled by Rac1 and Rac1b

Despite improvements in diagnosis and treatment, breast cancer is still the most common cancer type among non-smoking females. TGF-β can inhibit breast cancer development by inducing cell cycle arrest in both, cancer cells and, as part of a senescence program in normal human mammary epithelial cells...

詳細記述

保存先:
書誌詳細
出版年:Int J Mol Sci
主要な著者: Melzer, Catharina, von der Ohe, Juliane, Hass, Ralf, Ungefroren, Hendrik
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536062/
https://ncbi.nlm.nih.gov/pubmed/28726720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18071574
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