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Analysis of Hypericin-Mediated Effects and Implications for Targeted Photodynamic Therapy

The phototoxic effect of hypericin can be utilized for Photodynamic Therapy (PDT) of cancer. After intravenous application and systemic distribution of the drug in the patient’s body, the tumor site is exposed to light. Subsequently, toxic reactive oxygen species (ROS) are generated, inducing tumor...

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Publicat a:Int J Mol Sci
Autors principals: Mühleisen, Laura, Alev, Magdalena, Unterweger, Harald, Subatzus, Daniel, Pöttler, Marina, Friedrich, Ralf P., Alexiou, Christoph, Janko, Christina
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535881/
https://ncbi.nlm.nih.gov/pubmed/28661430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18071388
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