Treatment Efficiency of Free and Nanoparticle-Loaded Mitoxantrone for Magnetic Drug Targeting in Multicellular Tumor Spheroids

Major problems of cancer treatment using systemic chemotherapy are severe side effects. Magnetic drug targeting (MDT) employing superparamagnetic iron oxide nanoparticles (SPION) loaded with chemotherapeutic agents may overcome this dilemma by increasing drug accumulation in the tumor and reducing t...

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Publicado en:Molecules
Main Authors: Hornung, Annkathrin, Poettler, Marina, Friedrich, Ralf P., Zaloga, Jan, Unterweger, Harald, Lyer, Stefan, Nowak, Johannes, Odenbach, Stefan, Alexiou, Christoph, Janko, Christina
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6332068/
https://ncbi.nlm.nih.gov/pubmed/26437393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules201018016
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