Treatment Efficiency of Free and Nanoparticle-Loaded Mitoxantrone for Magnetic Drug Targeting in Multicellular Tumor Spheroids

Major problems of cancer treatment using systemic chemotherapy are severe side effects. Magnetic drug targeting (MDT) employing superparamagnetic iron oxide nanoparticles (SPION) loaded with chemotherapeutic agents may overcome this dilemma by increasing drug accumulation in the tumor and reducing t...

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Pubblicato in:Molecules
Autori principali: Hornung, Annkathrin, Poettler, Marina, Friedrich, Ralf P., Zaloga, Jan, Unterweger, Harald, Lyer, Stefan, Nowak, Johannes, Odenbach, Stefan, Alexiou, Christoph, Janko, Christina
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6332068/
https://ncbi.nlm.nih.gov/pubmed/26437393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules201018016
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