Superparamagnetic Iron Oxide Nanoparticles Carrying Chemotherapeutics Improve Drug Efficacy in Monolayer and Spheroid Cell Culture by Enabling Active Accumulation

Cytotoxic and cytostatic chemotherapeutics act by attacking rapidly dividing tumor cells, predominantly affecting malignant tissue and to a certain degree preserving healthy cells. Nonetheless, severe side effects are caused as quickly proliferating healthy cells such as hematopoietic precursors and...

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Bibliographic Details
Published in:Nanomaterials (Basel)
Main Authors: Nguyen, Khanh, Nuß, Bianca, Mühlberger, Marina, Unterweger, Harald, Friedrich, Ralf P., Alexiou, Christoph, Janko, Christina
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7466387/
https://ncbi.nlm.nih.gov/pubmed/32796757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano10081577
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