Loading of Primary Human T Lymphocytes with Citrate-Coated Superparamagnetic Iron Oxide Nanoparticles Does Not Impair Their Activation after Polyclonal Stimulation

For the conversion of immunologically cold tumors, characterized by a low T cell infiltration, into hot tumors, it is necessary to enrich T cells in the tumor area. One possibility is the use of magnetic fields to direct T cells into the tumor. For this purpose, primary T cells that were freshly iso...

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Detalhes bibliográficos
Main Authors: Marina Mühlberger, Harald Unterweger, Julia Band, Christian Lehmann, Lukas Heger, Diana Dudziak, Christoph Alexiou, Geoffrey Lee, Christina Janko
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-02-01
Colecção:Cells
Assuntos:
spion
t cells
nanomedicine
cancer
solid tumor
magnetic targeting
t cell activation
immune therapy
Acesso em linha:https://www.mdpi.com/2073-4409/9/2/342
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