Analysis of Hypericin-Mediated Effects and Implications for Targeted Photodynamic Therapy

The phototoxic effect of hypericin can be utilized for Photodynamic Therapy (PDT) of cancer. After intravenous application and systemic distribution of the drug in the patient’s body, the tumor site is exposed to light. Subsequently, toxic reactive oxygen species (ROS) are generated, inducing tumor...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Mühleisen, Laura, Alev, Magdalena, Unterweger, Harald, Subatzus, Daniel, Pöttler, Marina, Friedrich, Ralf P., Alexiou, Christoph, Janko, Christina
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535881/
https://ncbi.nlm.nih.gov/pubmed/28661430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18071388
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