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Analysis of Hypericin-Mediated Effects and Implications for Targeted Photodynamic Therapy

The phototoxic effect of hypericin can be utilized for Photodynamic Therapy (PDT) of cancer. After intravenous application and systemic distribution of the drug in the patient’s body, the tumor site is exposed to light. Subsequently, toxic reactive oxygen species (ROS) are generated, inducing tumor...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Mühleisen, Laura, Alev, Magdalena, Unterweger, Harald, Subatzus, Daniel, Pöttler, Marina, Friedrich, Ralf P., Alexiou, Christoph, Janko, Christina
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535881/
https://ncbi.nlm.nih.gov/pubmed/28661430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18071388
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