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Adult Ventricular Myocytes Segregate KCNQ1 and KCNE1 to Keep the I(Ks) Amplitude in Check until when Larger I(Ks) Is Needed

BACKGROUND: KCNQ1 and KCNE1 assemble to form the slow delayed rectifier (I(Ks)) channel critical for shortening ventricular action potentials during high β-adrenergic tone. However, too much I(Ks) under basal conditions poses an arrhythmogenic risk. Our objective is to understand how adult ventricul...

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Detalhes bibliográficos
Publicado no:Circ Arrhythm Electrophysiol
Main Authors: Jiang, Min, Wang, Yuhong, Tseng, Gea-Ny
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535779/
https://ncbi.nlm.nih.gov/pubmed/28611207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.117.005084
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