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[Ca(2+)](i) Elevation and Oxidative Stress Induce KCNQ1 Protein Translocation from the Cytosol to the Cell Surface and Increase Slow Delayed Rectifier (I(Ks)) in Cardiac Myocytes

Our goals are to simultaneously determine the three-dimensional distribution patterns of KCNQ1 and KCNE1 in cardiac myocytes and to study the mechanism and functional implications for variations in KCNQ1/KCNE1 colocalization in myocytes. We monitored the distribution patterns of KCNQ1, KCNE1, and ma...

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Autors principals: Wang, Yuhong, Zankov, Dimitar P., Jiang, Min, Zhang, Mei, Henderson, Scott C., Tseng, Gea-Ny
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853284/
https://ncbi.nlm.nih.gov/pubmed/24142691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.504746
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