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NAD(+) repletion improves muscle function in muscular dystrophy and counters global PARylation
Neuromuscular diseases are often caused by inherited mutations that lead to progressive skeletal muscle weakness and degeneration. In diverse populations of normal healthy mice, we observed correlations between the abundance of mRNA transcripts related to mitochondrial biogenesis, the dystrophin-sar...
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Publicado no: | Sci Transl Med |
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5535761/ https://ncbi.nlm.nih.gov/pubmed/27798264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaf5504 |
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