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NAD(+) metabolism and the control of energy homeostasis - a balancing act between mitochondria and the nucleus

NAD(+) has emerged as a vital cofactor that can rewire metabolism, activate sirtuins and maintain mitochondrial fitness through mechanisms such as the mitochondrial unfolded protein response. This improved understanding of NAD(+) metabolism revived interest in NAD(+) boosting strategies to manage a...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Cantó, Carles, Menzies, Keir, Auwerx, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487780/
https://ncbi.nlm.nih.gov/pubmed/26118927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.05.023
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