Type I Interferon Supports Inducible Nitric Oxide Synthase in Murine Hepatoma Cells and Hepatocytes and during Experimental Acetaminophen-Induced Liver Damage

Cytokine regulation of high-output nitric oxide (NO) derived from inducible NO synthase (iNOS) is critically involved in inflammation biology and host defense. Herein, we set out to characterize the role of type I interferon (IFN) as potential regulator of hepatic iNOS in vitro and in vivo. In this...

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Udgivet i:Front Immunol
Main Authors: Bachmann, Malte, Waibler, Zoe, Pleli, Thomas, Pfeilschifter, Josef, Mühl, Heiko
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5534483/
https://ncbi.nlm.nih.gov/pubmed/28824623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00890
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