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The Amyloid Precursor Protein Is a Conserved Receptor for Slit to Mediate Axon Guidance
The amyloid precursor protein (APP) is a receptor-like membrane protein. Although APP processing and β-amyloid production play a central role in Alzheimer’s disease (AD) pathogenesis, the physiological function of APP remains elusive. Here, we identify APP as a novel receptor for Slit that mediates...
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| Publicat a: | eNeuro |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Society for Neuroscience
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5534435/ https://ncbi.nlm.nih.gov/pubmed/28785723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0185-17.2017 |
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