The Amyloid Precursor Protein Is a Conserved Receptor for Slit to Mediate Axon Guidance

The amyloid precursor protein (APP) is a receptor-like membrane protein. Although APP processing and β-amyloid production play a central role in Alzheimer’s disease (AD) pathogenesis, the physiological function of APP remains elusive. Here, we identify APP as a novel receptor for Slit that mediates...

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Detalhes bibliográficos
Publicado no:eNeuro
Main Authors: Wang, Baiping, Li, Hongmei, Mutlu, Sena A., Bowser, Devon A., Moore, Michael J., Wang, Meng C., Zheng, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2017
Assuntos:
New Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5534435/
https://ncbi.nlm.nih.gov/pubmed/28785723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0185-17.2017
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