Diversity and Specificity of Actions of Slit2 Proteolytic Fragments in Axon Guidance

The Slits are secreted proteins that bind to Robo receptors and play a role in axon guidance and neuronal migration. In vertebrates, Slit2 is a major chemorepellent for developing axons and is involved in the control of midline crossing. In vivo, Slit2 is cleaved into 140 kDa N-terminal (Slit2-N) an...

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Publicado no:J Neurosci
Main Authors: Ba-Charvet, Kim T. Nguyen, Brose, Katja, Ma, Le, Wang, Kuan H., Marillat, Valérie, Sotelo, Constantino, Tessier-Lavigne, Marc, Chédotal, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2001
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762758/
https://ncbi.nlm.nih.gov/pubmed/11404413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-12-04281.2001
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