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The Amyloid Precursor Protein Controls Adult Hippocampal Neurogenesis through GABAergic Interneurons
Impaired neurogenesis in the adult hippocampus has been implicated in AD pathogenesis. Here we reveal that the APP plays an important role in the neural progenitor proliferation and newborn neuron maturation in the mouse dentate gyrus. APP controls adult neurogenesis through a noncell-autonomous mec...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4180470/ https://ncbi.nlm.nih.gov/pubmed/25274811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2848-14.2014 |
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