Discovery and Mechanistic Study of Benzamide Derivatives That Modulate Hepatitis B Virus Capsid Assembly

Chronic hepatitis B virus (HBV) infection is a global public health problem. Although the currently approved medications can reliably reduce the viral load and prevent the progression of liver diseases, they fail to cure the viral infection. In an effort toward discovery of novel antiviral agents ag...

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Veröffentlicht in:J Virol
Hauptverfasser: Wu, Shuo, Zhao, Qiong, Zhang, Pinghu, Kulp, John, Hu, Lydia, Hwang, Nicky, Zhang, Jiming, Block, Timothy M., Xu, Xiaodong, Du, Yanming, Chang, Jinhong, Guo, Ju-Tao
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533917/
https://ncbi.nlm.nih.gov/pubmed/28566379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00519-17
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