Interactions between HIV-1 Gag and Viral RNA Genome Enhance Virion Assembly

Most HIV-1 virions contain two copies of full-length viral RNA, indicating that genome packaging is efficient and tightly regulated. However, the structural protein Gag is the only component required for the assembly of noninfectious viruslike particles, and the viral RNA is dispensable in this proc...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Dilley, Kari A., Nikolaitchik, Olga A., Galli, Andrea, Burdick, Ryan C., Levine, Louis, Li, Kelvin, Rein, Alan, Pathak, Vinay K., Hu, Wei-Shau
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Structure and Assembly
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533913/
https://ncbi.nlm.nih.gov/pubmed/28539452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02319-16
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