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Interactions between HIV-1 Gag and Viral RNA Genome Enhance Virion Assembly

Most HIV-1 virions contain two copies of full-length viral RNA, indicating that genome packaging is efficient and tightly regulated. However, the structural protein Gag is the only component required for the assembly of noninfectious viruslike particles, and the viral RNA is dispensable in this proc...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Dilley, Kari A., Nikolaitchik, Olga A., Galli, Andrea, Burdick, Ryan C., Levine, Louis, Li, Kelvin, Rein, Alan, Pathak, Vinay K., Hu, Wei-Shau
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533913/
https://ncbi.nlm.nih.gov/pubmed/28539452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02319-16
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