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Gag-Dependent Enrichment of HIV-1 RNA near the Uropod Membrane of Polarized T Cells
The enrichment of HIV-1 macromolecules at the uropod of polarized T cells can significantly promote virus assembly and cell-mediated infection. Using live-cell fluorescence microscopy, we demonstrate that full-length HIV-1 RNA is enriched at the uropod membrane; furthermore, the presence of HIV-1 Ga...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3807364/ https://ncbi.nlm.nih.gov/pubmed/23966405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01680-13 |
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