HIV-1 RNA genome dimerizes on the plasma membrane in the presence of Gag protein

Retroviruses package a dimeric genome comprising two copies of the viral RNA. Each RNA contains all of the genetic information for viral replication. Packaging a dimeric genome allows the recovery of genetic information from damaged RNA genomes during DNA synthesis and promotes frequent recombinatio...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Chen, Jianbo, Rahman, Sheikh Abdul, Nikolaitchik, Olga A., Grunwald, David, Sardo, Luca, Burdick, Ryan C., Plisov, Sergey, Liang, Edward, Tai, Sheldon, Pathak, Vinay K., Hu, Wei-Shau
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
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PNAS Plus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720333/
https://ncbi.nlm.nih.gov/pubmed/26712001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1518572113
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