Novel Cross-Reactive Monoclonal Antibodies against Ebolavirus Glycoproteins Show Protection in a Murine Challenge Model

Out of an estimated 31,100 cases since their discovery in 1976, ebolaviruses have caused approximately 13,000 deaths. The vast majority (∼11,000) of these occurred during the 2013-2016 West African epidemic. Three out of five species in the genus are known to cause Ebola Virus Disease in humans. Sev...

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Veröffentlicht in:J Virol
Hauptverfasser: Duehr, James, Wohlbold, Teddy John, Oestereich, Lisa, Chromikova, Veronika, Amanat, Fatima, Rajendran, Madhusudan, Gomez-Medina, Sergio, Mena, Ignacio, tenOever, Benjamin R., García-Sastre, Adolfo, Basler, Christopher F., Munoz-Fontela, Cesar, Krammer, Florian
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533894/
https://ncbi.nlm.nih.gov/pubmed/28592526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00652-17
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