Novel Cross-Reactive Monoclonal Antibodies against Ebolavirus Glycoproteins Show Protection in a Murine Challenge Model

Out of an estimated 31,100 cases since their discovery in 1976, ebolaviruses have caused approximately 13,000 deaths. The vast majority (∼11,000) of these occurred during the 2013-2016 West African epidemic. Three out of five species in the genus are known to cause Ebola Virus Disease in humans. Sev...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Duehr, James, Wohlbold, Teddy John, Oestereich, Lisa, Chromikova, Veronika, Amanat, Fatima, Rajendran, Madhusudan, Gomez-Medina, Sergio, Mena, Ignacio, tenOever, Benjamin R., García-Sastre, Adolfo, Basler, Christopher F., Munoz-Fontela, Cesar, Krammer, Florian
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533894/
https://ncbi.nlm.nih.gov/pubmed/28592526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00652-17
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