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Epigenetic changes in myelofibrosis: Distinct methylation changes in the myeloid compartments and in cases with ASXL1 mutations

This is the first study to compare genome-wide DNA methylation profiles of sorted blood cells from myelofibrosis (MF) patients and healthy controls. We found that differentially methylated CpG sites located to genes involved in ‘cancer’ and ‘embryonic development’ in MF CD34+ cells, in ‘inflammatory...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Rep
मुख्य लेखकों: Nielsen, Helene Myrtue, Andersen, Christen Lykkegaard, Westman, Maj, Kristensen, Lasse Sommer, Asmar, Fazila, Kruse, Torben Arvid, Thomassen, Mads, Larsen, Thomas Stauffer, Skov, Vibe, Hansen, Lise Lotte, Bjerrum, Ole Weis, Hasselbalch, Hans Carl, Punj, Vasu, Grønbæk, Kirsten
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533802/
https://ncbi.nlm.nih.gov/pubmed/28754985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07057-3
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