Whole-exome sequencing and genome-wide methylation analyses identify novel disease associated mutations and methylation patterns in idiopathic hypereosinophilic syndrome

A thorough understanding of the idiopathic hypereosinophilic syndrome (IHES) and further optimization of diagnostic work-up procedures are warranted. We analyzed purified eosinophils from patients with IHES by next-generation whole-exome sequencing and compared DNA methylation profiles from reactive...

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Publicado en:Oncotarget
Autores principales: Andersen, Christen Lykkegaard, Nielsen, Helene Myrtue, Kristensen, Lasse Sommer, Søgaard, Alexandra, Vikeså, Jonas, Jønson, Lars, Nielsen, Finn Cilius, Hasselbalch, Hans, Bjerrum, Ole Weis, Punj, Vasu, Grønbæk, Kirsten
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747354/
https://ncbi.nlm.nih.gov/pubmed/26497854
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