Whole Blood Transcriptional Profiling Reveals Deregulation of Oxidative and Antioxidative Defence Genes in Myelofibrosis and Related Neoplasms. Potential Implications of Downregulation of Nrf2 for Genomic Instability and Disease Progression

The Philadelphia-negative chronic myeloproliferative neoplasms - essential thrombocythemia (ET), polycythemia vera (PV), and myelofibrosis (MF) (MPNs) - have recently been shown to be associated with chronic inflammation, oxidative stress and accumulation of reactive oxygen species (ROS). Using whol...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hasselbalch, Hans Carl, Thomassen, Mads, Hasselbalch Riley, Caroline, Kjær, Lasse, Stauffer Larsen, Thomas, Jensen, Morten K., Bjerrum, Ole Weis, Kruse, Torben A., Skov, Vibe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232509/
https://ncbi.nlm.nih.gov/pubmed/25397683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112786
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